April 25, 2020 - March 31, 2022 - Addressing safety issues by quantify large deletions and chromosomal rearrangements in HBB gene editing , Co-Investigator . Sponsor: NIH, Sponsor Award ID: OT2HL154977
September 1, 2015 - July 31, 2021 - Hematopoietic Stem Cell Transplantation for Young Adults with Sickle Cell Disease - Clinical Coordinating Center , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01HL128566
September 20, 2019 - June 30, 2021 - Clinical Microfluidic Assessment of Red Blood Cell Adhesion, Deformability, Cellular Hemoglobin Distribution, Cellular Density, and Blood Rheology for Curative Therapies in Sickle Cell Disease , Co-Investigator . Sponsor: NIH, Sponsor Award ID: OT2HL152643
June 12, 2019 - May 31, 2021 - Curing Sickle Cell Disease with CRISPR-Cas9 genome editing , Principal Investigator . Sponsor: NIH, Sponsor Award ID: OT2HL151319
September 1, 2011 - April 30, 2016 - Hematopoietic Cell Therapy for Young Adults with Severe Sickle Cell Disease , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R34HL108761
April 18, 2006 - March 31, 2011 - Northern California Consortium for Sickle Cell Disease , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U10HL083704
August 25, 2001 - July 31, 2007 - Induction of Stable Chimerism for Sickle Cell Anemia , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01HL068091
July 10, 1998 - June 30, 2002 - MECHANISMS OF GLOBIN GENE SILENCING , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R29HL060927
August 1, 1992 - June 30, 2001 - GLOBIN GENE REGULATION BY GATA-1 AND CHROMATIN , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01HL048790
July 1, 1994 - June 30, 1999 - MECHANISMS OF ERYTHROID GENE EXPRESSION , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K08HL003098