Education

University of Washington, Seattle, BS, 06/2004, (Magna Cum Laude) Biochemistry
University of North Carolina at Chapel Hill, MD, 05/2012, Medicine
University of North Carolina at Chapel Hill, PhD, 06/2010, Microbiology and Immunology
Hospital of the University of Pennsylvania, Resident, 07/2013, Internal Medicine
University of Pennsylvania, Postdoctoral Associate, 05/2014, Hematology
University of California, San Francisco, Resident, 06/2016, Pathology
University of California, San Francisco, Fellow, 06/2017, Hematopathology
University of California, San Francisco, Fellow/Chief Resident, 06/2018, Gastrointestinal/ Liver Pathology

Honors & Awards

  • 2001
    Mary Gates Scholarship
  • 2002
    Ronald E. McNair Presidential Scholarship
  • 2003
    Herschel and Caryl Roman Undergraduate Science Scholarship
  • 2004
    American Institute of Chemists Foundation Student Award
  • 2004
    Phi Beta Kappa
  • 2004
    Distinction in Biochemistry
  • 2004
    Medical Scientist Training Program
  • 2006
    Harold C. Pillsbury, M.D. Student Research Award
  • 2009
    Lineberger Annual Scientific Competition Winner
  • 2010
    University Cancer Research Fund Scholarship
  • 2010
    Annual G. Philip Manire Graduate Student Excellence in Research Award
  • 2010
    Lineberger Comprehensive Cancer Center Graduate Fellow Award in Basic Sciences
  • 2017
    Best Abstract Award, International Association of Chinese Pathologists
  • 2017
    Arthur Purdy Stout Stipend Award
  • 2018
    Best Abstract Award (2nd place in platform), Chinese American Pathologists Association
  • 2018
    Best Abstract Award (runner up), Rodger C. Haggitt Gastrointestinal Pathology Society
  • 2019
    F. Stephen Vogel Award, United States and Canadian Academy of Pathology
  • 2022
    Faculty Teaching Award, UCSF Department of Pathology

Selected Publications

  1. Majd H, Samuel RM, Cesiulis A, Ramirez JT, Kalantari A, Barber K, Farahvashi S, Ghazizadeh Z, Majd A, Chemel AK, Richter MN, Das S, Bendrick JL, Keefe MG, Wang J, Shiv RK, Bhat S, Khoroshkin M, Yu J, Nowakowski TJ, Wen KW, Goodarzi H, Thapar N, Kaltschmidt JA, McCann CJ, Fattahi F. Engrafted nitrergic neurons derived from hPSCs improve gut dysmotility in mice. Nature. 2025 Jun 25.  View on PubMed
  2. Rademaker G, Hernandez GA, Seo Y, Dahal S, Miller-Phillips L, Li AL, Peng XL, Luan C, Qiu L, Liegeois MA, Wang B, Wen KW, Kim GE, Collisson EA, Kruger SF, Boeck S, Ormanns S, Guenther M, Heinemann V, Haas M, Looney MR, Yeh JJ, Zoncu R, Perera RM. PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. 2025 May 21.  View on PubMed
  3. Choi JE, Valle R, Long-Boyle J, Garcia BM, Frieden IJ, Pincus LB, Akagi N, Bhargava P, Wen KW, Ozgediz D, Rangaswami A, Chu J, Levinson A, Avagyan S. KIT Inhibitor Therapy in a Pediatric Patient With Systemic Mastocytosis and a Germ Cell Tumor of Shared Clonal Origin. Pediatr Blood Cancer. 2025 Jul; 72(7):e31717.  View on PubMed
  4. Geng H, Mo S, Chen L, Ballapuram A, Tsang M, Lu M, Rauschecker AM, Wen KW, Devine WP, Solomon DA, Rubenstein JL. Identification of genomic biomarkers of disease progression and survival in primary CNS lymphoma. Blood Adv. 2025 Mar 11; 9(5):1117-1131.  View on PubMed
  5. Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. Functional screen identifies RBM42 as a mediator of oncogenic mRNA translation specificity. Nat Cell Biol. 2025 Mar; 27(3):518-529.  View on PubMed
  6. Nguyen ED, Wen KW, Kakar S, Balitzer DJ. Clinicopathologic features and outcomes of hepatic inflammatory pseudotumour (IPT) and hepatic IPT-like lesions. Histopathology. 2025 Mar; 86(4):525-535.  View on PubMed
  7. Leet DE, Wen KW, Kouanda A. Should We Rest on a Rest? A Well-Differentiated Neuroendocrine Tumor Arising From Pancreatic Heterotopia. Am J Gastroenterol. 2024 Oct 17.  View on PubMed
  8. Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. Functional screen for mediators of onco-mRNA translation specificity. bioRxiv. 2024 Oct 11.  View on PubMed
  9. Nguyen ED, Ding CC, Umetsu SE, Ferrell LD, Wen KW. Glutamine synthetase staining patterns in cirrhosis. Hum Pathol. 2024 Nov; 153:105655.  View on PubMed
  10. Kumar A, Rara M, Yu M, Wen KW, Grady WM, Chak A, Iyer PG, Rustgi AK, Wang TC, Rubenstein JH, Liu Y, Kresty L, Westerhoff M, Kwon RS, Wamsteker E, Wang T, Berry L, Canto MI, Shaheen NJ, Wang KK, Abrams JA, Stachler MD. Molecular Analysis of Persistent and Recurrent Barrett's Esophagus in the Setting of Endoscopic Therapy. Clin Transl Gastroenterol. 2024 Aug 01; 15(8):e00751.  View on PubMed
  11. Craig A, Güney E, Pekmezci M, Bloomer M, Laszik Z, Ohgami RS, Toland A, Vogel H, Forns T, Wang E, Rubenstein J, Wen KW. Utility of PD-1, PD-L1, and IDO-1 Stains in Ocular Extranodal Marginal Zone Lymphoma (MZL) and Diffuse Large B-cell Lymphoma (DLBCL). Appl Immunohistochem Mol Morphol. 2024 Sep 01; 32(8):395-399.  View on PubMed
  12. Hu S, Graham RP, Choi WT, Wen KW, Putra J, Chen W, Lin J, Gonzalez IA, Panarelli N, Liu Q, Zhao L, Gong S, Mejia-Bautista M, Escobar DJ, Ma C, Shalaby A, Du X, Kang LI, Zhang W, Chen X, Ding X, Chen HH, Ye Z, Pezhouh MK, Liao X, Liu Y, Yang Z, Alpert L, Hart J, Goldblum JR, Allende D, Zheng W, Gonzalez RS, Wang HL, Zhang X, Liu X, Longacre T, Westerhoff M, Xue Y. Clinicopathologic Features of Gastrointestinal Tract Langerhans Cell Histiocytosis. Mod Pathol. 2024 Sep; 37(9):100543.  View on PubMed
  13. Wen KW, Kakar S. Hepatic Precancerous Lesions and Early Hepatocellular Carcinoma. Gastroenterol Clin North Am. 2024 03; 53(1):109-132.  View on PubMed
  14. Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T. Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer. Cancer Cell. 2023 11 13; 41(11):1989-2005.e9.  View on PubMed
  15. Saglam A, Singh K, Kumar J, Gollapudi S, Mukherjee S, Singh A, Butzmann A, Kaplan L, Andreadis C, Ai WZ, Fakhri B, Rajkovic A, Wen KW, Onodera C, Van Ziffle J, Devine PW, Ohgami RS. Copy Number Loss at Chromosome 14q11.2 Correlates With the Proportion of T Cells in Biopsies and Helps Identify T-Cell Neoplasms. Arch Pathol Lab Med. 2023 08 01; 147(8):940-948.  View on PubMed
  16. Guney E, Lucas CG, Singh K, Pekmezci M, Fernandez-Pol S, Mirchia K, Toland A, Vogel H, Bannykh S, Schafernak KT, Alexandrescu S, Mobley BC, Powell S, Davidson CJ, Neltner J, Boué DR, Hattab E, Ferris SP, Ohgami RS, Rubenstein JL, Bollen AW, Tihan T, Perry A, Solomon DA, Wen KW. Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS. Blood Adv. 2023 07 11; 7(13):3307-3311.  View on PubMed
  17. Nguyen ED, Ding CC, Umetsu SE, Choi WT, Ferrell LD, Wen KW. Use of orcein as an adjunct stain in the evaluation of advanced liver fibrosis. Histopathology. 2023 Oct; 83(4):538-545.  View on PubMed
  18. Craig A, Wen KW. ALK+ ALCL in the setting of adalimumab-related hidradenitis suppurativa. Clin Case Rep. 2023 Apr; 11(4):e7156.  View on PubMed
  19. Joseph NM, Wen KW. Incidental Langerhans cell histiocytosis associated with metastatic neuroendocrine tumor in the adult liver. Clin Case Rep. 2023 Feb; 11(2):e6922.  View on PubMed
  20. Umetsu SE, Kakar S, Basturk O, Kim GE, Chatterjee D, Wen KW, Hale G, Shafizadeh N, Cho SJ, Whitman J, Gill RM, Jones KD, Navale P, Bergsland E, Klimstra D, Joseph NM. Integrated Genomic and Clinicopathologic Approach Distinguishes Pancreatic Grade 3 Neuroendocrine Tumor From Neuroendocrine Carcinoma and Identifies a Subset With Molecular Overlap. Mod Pathol. 2023 03; 36(3):100065.  View on PubMed

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