University of Southern California, B.S., 05/2009, Chemistry
University of Southern California, Ph.D., 06/2014, Chemical Biology
The Scripps Research Institute, Postdoctoral, 09/2017, Chemical Biology
Stanford School of Medicine, Postdoctoral, 08/2019, Stem Cell Biology and Innate Immunity

Selected Publications

  1. Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR. Correction to "Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification". J Am Chem Soc. 2023 Sep 29.  View on PubMed
  2. Sapiro AL, Hayes BM, Volk RF, Zhang JY, Brooks DM, Martyn C, Radkov A, Zhao Z, Kinnersley M, Secor PR, Zaro BW, Chou S. Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission. Elife. 2023 Jul 14; 12.  View on PubMed
  3. Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL. EMC chaperone-CaV structure reveals an ion channel assembly intermediate. Nature. 2023 Jul; 619(7969):410-419.  View on PubMed
  4. Datta R, Gholampour MA, Yang CD, Volk R, Lin S, Podolsky MJ, Arnold T, Rieder F, Zaro BW, Verzi M, Lehner R, Abumrad N, Lizama CO, Atabai K. MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes. Cell Rep. 2023 03 28; 42(3):112249.  View on PubMed
  5. Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Volk RF, Hofmann KL, Zaro B, Chuang PT. Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions. PLoS Biol. 2022 08; 20(8):e3001759.  View on PubMed
  6. Dang EV, Lei S, Radkov A, Volk RF, Zaro BW, Madhani HD. Secreted fungal virulence effector triggers allergic inflammation via TLR4. Nature. 2022 08; 608(7921):161-167.  View on PubMed
  7. Montaño JL, Wang BJ, Volk RF, Warrington SE, Garda VG, Hofmann KL, Chen LC, Zaro BW. Improved Electrophile Design for Exquisite Covalent Molecule Selectivity. ACS Chem Biol. 2022 06 17; 17(6):1440-1449.  View on PubMed
  8. Volk RF, Montaño JL, Warrington SE, Hofmann KL, Zaro BW. Proteomic characterization of phagocytic primary human monocyte-derived macrophages. RSC Chem Biol. 2022 Jun 08; 3(6):783-793.  View on PubMed
  9. Bouffard E, Zaro BW, Dix MM, Cravatt B, Wong CH. Refinement of Covalent EGFR Inhibitor AZD9291 to Eliminate Off-target Activity. Tetrahedron Lett. 2021 Jun 22; 74.  View on PubMed
  10. Zaro BW, Noh JJ, Mascetti VL, Demeter J, George B, Zukowska M, Gulati GS, Sinha R, Flynn RA, Banuelos A, Zhang A, Wilkinson AC, Jackson P, Weissman IL. Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells. Elife. 2020 11 25; 9.  View on PubMed
  11. Pedowitz NJ, Zaro BW, Pratt MR. Metabolic Labeling for the Visualization and Identification of Potentially O-GlcNAc-Modified Proteins. Curr Protoc Chem Biol. 2020 06; 12(2):e81.  View on PubMed
  12. Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR. O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Front Chem. 2020; 8:318.  View on PubMed
  13. Barkal AA, Brewer RE, Markovic M, Kowarsky M, Barkal SA, Zaro BW, Krishnan V, Hatakeyama J, Dorigo O, Barkal LJ, Weissman IL. CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. Nature. 2019 08; 572(7769):392-396.  View on PubMed
  14. Senkane K, Vinogradova EV, Suciu RM, Crowley VM, Zaro BW, Bradshaw JM, Brameld KA, Cravatt BF. The Proteome-Wide Potential for Reversible Covalency at Cysteine. Angew Chem Int Ed Engl. 2019 08 12; 58(33):11385-11389.  View on PubMed
  15. Zaro BW, Vinogradova EV, Lazar DC, Blewett MM, Suciu RM, Takaya J, Studer S, de la Torre JC, Casanova JL, Cravatt BF, Teijaro JR. Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex. J Immunol. 2019 05 01; 202(9):2737-2746.  View on PubMed
  16. Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway. Chembiochem. 2018 09 17; 19(18):1918-1921.  View on PubMed
  17. Bateman LA, Zaro BW, Miller SM, Pratt MR. Correction to "An Alkyne-Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells". J Am Chem Soc. 2018 04 11; 140(14):4954.  View on PubMed
  18. Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8. J Am Chem Soc. 2017 06 14; 139(23):7872-7885.  View on PubMed
  19. Batt AR, Zaro BW, Navarro MX, Pratt MR. Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling. Chembiochem. 2017 07 04; 18(13):1177-1182.  View on PubMed
  20. Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR. The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase. ACS Chem Biol. 2017 03 17; 12(3):787-794.  View on PubMed

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