Education

University of Southern California, B.S., 05/2009, Chemistry
University of Southern California, Ph.D., 06/2014, Chemical Biology
The Scripps Research Institute, Postdoctoral, 09/2017, Chemical Biology
Stanford School of Medicine, Postdoctoral, 08/2019, Stem Cell Biology and Innate Immunity

Selected Publications

  1. Zaro BW, Noh JJ, Mascetti VL, Demeter J, George B, Zukowska M, Gulati GS, Sinha R, Flynn RA, Banuelos A, Zhang A, Wilkinson AC, Jackson P, Weissman IL Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells.  View on PubMed
  2. Pedowitz NJ, Zaro BW, Pratt MR Metabolic Labeling for the Visualization and Identification of Potentially O-GlcNAc-Modified Proteins.  View on PubMed
  3. Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins.  View on PubMed
  4. Barkal AA, Brewer RE, Markovic M, Kowarsky M, Barkal SA, Zaro BW, Krishnan V, Hatakeyama J, Dorigo O, Barkal LJ, Weissman IL CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.  View on PubMed
  5. Senkane K, Vinogradova EV, Suciu RM, Crowley VM, Zaro BW, Bradshaw JM, Brameld KA, Cravatt BF The Proteome-Wide Potential for Reversible Covalency at Cysteine.  View on PubMed
  6. Zaro BW, Vinogradova EV, Lazar DC, Blewett MM, Suciu RM, Takaya J, Studer S, de la Torre JC, Casanova JL, Cravatt BF, Teijaro JR Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex.  View on PubMed
  7. Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway.  View on PubMed
  8. Bateman LA, Zaro BW, Miller SM, Pratt MR Correction to "An Alkyne-Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells".  View on PubMed
  9. Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.  View on PubMed
  10. Batt AR, Zaro BW, Navarro MX, Pratt MR Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling.  View on PubMed
  11. Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.  View on PubMed
  12. Zaro BW, Whitby LR, Lum KM, Cravatt BF Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.  View on PubMed
  13. Blewett MM, Xie J, Zaro BW, Backus KM, Altman A, Teijaro JR, Cravatt BF Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.  View on PubMed
  14. Marotta NP, Lin YH, Lewis YE, Ambroso MR, Zaro BW, Roth MT, Arnold DB, Langen R, Pratt MR O-GlcNAc modification blocks the aggregation and toxicity of the protein a-synuclein associated with Parkinson's disease.  View on PubMed
  15. Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS Chemoproteomics reveals Toll-like receptor fatty acylation.  View on PubMed
  16. Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.  View on PubMed
  17. Zaro BW, Chuh KN, Pratt MR Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification.  View on PubMed
  18. Gurel Z, Zaro BW, Pratt MR, Sheibani N Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.  View on PubMed
  19. Bateman LA, Zaro BW, Miller SM, Pratt MR An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.  View on PubMed
  20. Zaro BW, Hang HC, Pratt MR Incorporation of unnatural sugars for the identification of glycoproteins.  View on PubMed

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