Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Read more about Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease.
Synthesis and evaluation of constrained phosphoramidate inhibitors of prostate-specific membrane antigen. Read more about Synthesis and evaluation of constrained phosphoramidate inhibitors of prostate-specific membrane antigen.
2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway. Read more about 2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors. Read more about Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors.
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors. Read more about Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors.
Novel cinnoline-based inhibitors of LRRK2 kinase activity. Read more about Novel cinnoline-based inhibitors of LRRK2 kinase activity.
A small molecule that preferentially binds the closed conformation of Hsp90. Read more about A small molecule that preferentially binds the closed conformation of Hsp90.
Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells. Read more about Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells.
Highly selective c-Jun N-terminal kinase (JNK) 3 inhibitors with in vitro CNS-like pharmacokinetic properties II. Central core replacement. Read more about Highly selective c-Jun N-terminal kinase (JNK) 3 inhibitors with in vitro CNS-like pharmacokinetic properties II. Central core replacement.
Robust in-gel fluorescence detection of mucin-type O-linked glycosylation. Read more about Robust in-gel fluorescence detection of mucin-type O-linked glycosylation.
