A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Read more about A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.
A hormone-DNA repair circuit governs the response to genotoxic insult. Read more about A hormone-DNA repair circuit governs the response to genotoxic insult.
Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death. Read more about Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death.
Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer. Read more about Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer.
Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation. Read more about Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.
G34, another connection between MYCN and a pediatric tumor. Read more about G34, another connection between MYCN and a pediatric tumor.
Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer. Read more about Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.
Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. Read more about Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Read more about Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers.
