Mouse models address key concerns regarding autophagy inhibition in cancer therapy. Read more about Mouse models address key concerns regarding autophagy inhibition in cancer therapy.
Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199. Read more about Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.
An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor. Read more about An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Read more about Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion.
MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction. Read more about MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction.
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Read more about Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets.
Q&A: Elizabeth Blackburn on telomerase and tumors. Read more about Q&A: Elizabeth Blackburn on telomerase and tumors.
Epithelial-to-mesenchymal transition rewires the molecular path to PI3K-dependent proliferation. Read more about Epithelial-to-mesenchymal transition rewires the molecular path to PI3K-dependent proliferation.
New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization. Read more about New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization.
