Therapeutic insights from genomic studies of head and neck squamous cell carcinomas. Read more about Therapeutic insights from genomic studies of head and neck squamous cell carcinomas.
The genetics of splicing in neuroblastoma. Read more about The genetics of splicing in neuroblastoma.
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Read more about Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis. Read more about The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Development of siRNA payloads to target KRAS-mutant cancer. Read more about Development of siRNA payloads to target KRAS-mutant cancer.
Mouse models address key concerns regarding autophagy inhibition in cancer therapy. Read more about Mouse models address key concerns regarding autophagy inhibition in cancer therapy.
An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor. Read more about An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Read more about Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion.
MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction. Read more about MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction.