De novo designed Hsp70 activator dissolves intracellular condensates. Read more about De novo designed Hsp70 activator dissolves intracellular condensates.
Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α. Read more about Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α.
Development of covalent chemogenetic K2P channel activators. Read more about Development of covalent chemogenetic K2P channel activators.
Molecular glues for protein-protein interactions: Progressing toward a new dream. Read more about Molecular glues for protein-protein interactions: Progressing toward a new dream.
Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells. Read more about Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells.
In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin. Read more about In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin.
Proteasome inhibitors: The next generation of antimalarial drugs? Read more about Proteasome inhibitors: The next generation of antimalarial drugs?
IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Read more about IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma. Read more about Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma.
A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities. Read more about A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities.
