News
Remote Control' of Immune Cells Opens Door to Safer, More Precise Cancer Therapies
UC San Francisco researchers have engineered a molecular “on switch” that allows tight control over the actions of T cells, immune system cells that have shown great potential as therapies for cancer. The innovation lays the groundwork for sharply reducing severe, sometimes deadly side effects that
Metastatic Breast Cancer Cells Turn On Stem Cell Genes
It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for years, only to trigger a recurrence decades after the primary tumor is
Building Human Breast Tissue, Cell by Cell
The next frontier in developing therapies for cancer and other diseases could come through studying organ development or tumor growth in living humans. Problem is, there’s no ethical way of doing that using current technology. Zev Gartner, PhD, has focused on the next best thing: His lab is building
Around The World, Those Treated for Addiction Far More Likely to Smoke
People in addiction treatment programs around the world use tobacco at two to three times the rate of people who are not being treated for addiction, according to a review of research studies from 20 countries other than the United States. The review, led by Joseph R. Guydish, PhD, a UC San
Antibody Network Partners With Celgene for Cancer Therapies
A new collaboration between Celgene Corp. and the Recombinant Antibody Network (RAN), a consortium comprising research groups from UC San Francisco (UCSF), the University of Chicago and the University of Toronto, will support the development of next-generation, antibody-based cancer therapies. In
Crunching Numbers to Combat Cancer
UC San Francisco has received a National Cancer Institute grant of $5 million over the next five years to lead a massive effort to integrate the data from all experimental models across all types of cancer. The web-based repository is an important step in moving the fight against cancer toward
Smoke-Free Zones, Higher Taxes Deter Youth Smoking, Study Shows
Banning smoking in the workplace and increasing taxes on cigarettes have discouraged teens and young adults from taking up smoking, according to a study by researchers at UC San Francisco and UC Merced. The study, published Sept. 8, in JAMA Pediatrics, used data on the smoking habits of a group of