Research Summary

Dr. Stephanie Cham’s primary research focus is to reduce disparities and improve perioperative care for gynecologic cancer patients, particularly in vulnerable populations, through innovative healthcare services outcomes research and the development of novel and scalable interventions including those leveraging new care delivery approaches and technology.

Dr. Stephanie Cham joins the faculty practice as a National Institute of Health Women’s Reproductive Health Research scholar, with a focus on how we can optimize cancer care delivery, particularly in frail and elderly patients. Her prior work has been presented at national conferences and published in journals including JAMA Oncology, American Journal of Obstetrics and Gynecology, Gynecologic Oncology, JAMA Network Open, and Obstetrics and Gynecology. Her clinical interests include providing exceptional and high-quality surgical care to patients as well as teaching trainees.

Research Funding

  • September 1, 2024 - August 31, 2026 - Promoting gynecologic cancer patients with frailty to achieve functional recovery cohort study (PROOF Cohort Study) , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R03AG088902
  • September 30, 1998 - June 30, 2025 - Women's Reproductive Health Research , K12 Scholar . Sponsor: NIH, Sponsor Award ID: K12HD001262

Education

MS, 12/2024 - Clinical and Epidemiologic Research, University of California San Francisco
Fellowship, 2022 - , Brigham and Women's Hospital/Dana-Farber Cancer Institute
10/2022 - Diversity, Equity, and Inclusion Champion Training, University of California San Francisco
Residency, 2019 - , Columbia University
MD, 2015 - , UCLA David Geffen School of Medicine

Honors & Awards

  • 2017 - Excellence in Teaching Award, Department of Obstetrics and Gynecology, CUMC
  • 2019 - Society of Gynecologic Oncology Outstanding Resident Award, CUMC
  • 2020 - Foundation for Women’s Cancer Laura Crandall Brown Research Grant, BWH
  • 2021 - Dana-Farber Berkman Family Fund Awardee
  • 2022 - American Society of Clinical Oncology Young Investigator Award in Ovarian Cancer Grant
  • 2023 - UCSF Outstanding Faculty Award in Medical Student Teaching
  • 2023 - UCSF Dedication to Medical Student Feedback Award
  • 2023 - Clin-STAR Travel Award
  • 2023-2024 - UCSF Obstetrics and Gynecology Research Mentor Award
  • 2024 - Society of Gynecologic Oncology BRIDGES Scholar

Selected Publications

  1. Charewycz NE, Hsu IJ, Lu K, Fuh K, Chen LM, Monga V, Cham S Complete response of somatic POLE-ultramutated recurrent undifferentiated uterine sarcoma to pembrolizumab and concurrent radiotherapy.  View on PubMed
  2. Cham S, Xiong N, Tayob N, Krasner C, Wright AA, Lee EK, Sawyer H, Mathews C, Konstantinopoulos PA, Matulonis UA, Liu JF Phase 2 study of Wee1 inhibitor adavosertib in recurrent uterine carcinosarcoma.  View on PubMed
  3. Cham S, Kumar A, Walter LC, Lichtman S, Tew WP. Understanding frailty and the role of patient-centered care for older adults with gynecologic cancer. Gynecol Oncol. 2025 May; 196:42-53.  View on PubMed
  4. Mvemba A, Liang J, Swanson M, Yoshida E, Ueda S, Fuh K, Chen LM, Cham S. Fragmented Care and Guideline-Concordant Treatment in Locally Advanced Cervical Cancer. Obstet Gynecol. 2025 Apr 01; 145(4):387-394.  View on PubMed
  5. Liang J, Mvemba A, Swanson M, Hsu IJ, Alvarez E, Chapman J, Fuh K, Chen LM, Cham S. Delay to timely treatment in locally advanced cervical cancer: insurance inequities in access to gynecologic oncology. Am J Obstet Gynecol. 2025 Feb 20.  View on PubMed
  6. Cham S, Pozzar RA, Horowitz N, Feltmate C, Matulonis UA, Lai JC, Wright AA. The pervasive impact of frailty on ovarian cancer care and the role of prehabilitation: Qualitative perspectives of key stakeholders. J Geriatr Oncol. 2025 Mar; 16(2):102173.  View on PubMed
  7. Cham S, Wright J. Fragmented Surgical Cancer Care-A Growing Divide. JCO Oncol Pract. 2024 Dec; 20(12):1788-1789.  View on PubMed
  8. Cham S, Landrum MB, Keating NL, Armstrong J, Wright AA. Use of Germline BRCA Testing in Patients With Ovarian Cancer and Commercial Insurance. JAMA Netw Open. 2022 01 04; 5(1):e2142703.  View on PubMed
  9. Cham S, Li A, Rauh-Hain JA, Tergas AI, Hershman DL, Wright JD, Melamed A. Association Between Neighborhood Socioeconomic Inequality and Cervical Cancer Incidence Rates in New York City. JAMA Oncol. 2022 01 01; 8(1):159-161.  View on PubMed
  10. Manning-Geist B, Cathcart AM, Sullivan MW, Pelletier A, Cham S, Muto MG, Del Carmen M, Growdon WB, Sisodia RC, Berkowitz R, Worley M. Predictive validity of American College of Surgeons: National Surgical Quality Improvement Project risk calculator in patients with ovarian cancer undergoing interval debulking surgery. Int J Gynecol Cancer. 2021 10; 31(10):1356-1362.  View on PubMed
  11. Cham S, Huang Y, Melamed A, Worley MJ, Hou JY, Tergas AI, Khoury-Collado F, Gockley A, Clair CMST, Hershman DL, Wright JD. Fragmentation of surgery and chemotherapy in the initial phase of ovarian cancer care and its association with overall survival. Gynecol Oncol. 2021 07; 162(1):56-64.  View on PubMed
  12. Krenitsky N, Wen T, Cham S, Venkatesh KK, Attenello F, Mack WJ, D'Alton M, Friedman AM. Hospital Admissions from the Emergency Department and Subsequent Critical Care Interventions for Influenza during Pregnancy. Am J Perinatol. 2023 02; 40(3):326-332.  View on PubMed
  13. Sia TY, Wen T, Cham S, Friedman AM, Wright JD. The effect of frailty on postoperative readmissions, morbidity, and mortality in endometrial cancer surgery. Gynecol Oncol. 2021 05; 161(2):353-360.  View on PubMed
  14. Straubhar AM, Wolf JL, Zhou MQC, Iasonos A, Cham S, Wright JD, Long Roche K, Chi DS, Zivanovic O. Advanced ovarian cancer and cytoreductive surgery: Independent validation of a risk-calculator for perioperative adverse events. Gynecol Oncol. 2021 02; 160(2):438-444.  View on PubMed
  15. Sia TY, Wen T, Cham S, Friedman AM, Wright JD. Effect of frailty on postoperative readmissions and cost of care for ovarian cancer. Gynecol Oncol. 2020 11; 159(2):426-433.  View on PubMed
  16. Cham S, Wen T, Friedman A, Wright JD. Fragmentation of postoperative care after surgical management of ovarian cancer at 30 days and 90 days. Am J Obstet Gynecol. 2020 03; 222(3):255.e1-255.e20.  View on PubMed
  17. Cham S, Chen L, St Clair CM, Hou JY, Tergas AI, Melamed A, Ananth CV, Neugut AI, Hershman DL, Wright JD. Development and validation of a risk-calculator for adverse perioperative outcomes for women with ovarian cancer. Am J Obstet Gynecol. 2019 06; 220(6):571.e1-571.e8.  View on PubMed
  18. Cham S, Huang Y, Tergas AI, Hou JY, Burke WM, Deutsch I, Ananth CV, Neugut AI, Hershman DL, Wright JD. Utility of radiation therapy for early-stage uterine papillary serous carcinoma. Gynecol Oncol. 2017 05; 145(2):269-276.  View on PubMed
  19. Wright JD, Cham S, Chen L, Burke WM, Hou JY, Tergas AI, Desai V, Hu JC, Ananth CV, Neugut AI, Hershman DL. Utilization of sentinel lymph node biopsy for uterine cancer. Am J Obstet Gynecol. 2017 06; 216(6):594.e1-594.e13.  View on PubMed
  20. Cham S, Koslik HJ, Golomb BA. Mood, Personality, and Behavior Changes During Treatment with Statins: A Case Series. Drug Saf Case Rep. 2016 Dec; 3(1):1.  View on PubMed

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