Education

  • 2022, Radiation Oncology Residency
    University of California, San Francisco
  • 2018, Preliminary Medicine Internship
    St. Mary’s Medical Center
  • 2017, MD, PhD
    University of Pennsylvania, School of Medicine
  • 2008, AB
    Harvard University

Honors & Awards

  • 2024
    Irving Cancer Immunology Symposium, selected attendee
  • 2022
    Society for Immunotherapy of Cancer 2022 Annual Meeting Young Investigator Travel Award
  • 2020-2021
    Chief Resident, UCSF Radiation Oncology
  • 2018
    American Board of Radiology Holman Research Pathway Fellow
  • 2018
    Florence Howe Outstanding Medical Intern Award, St. Mary's Medical Center
  • 2016
    Saul Winegrad Award for Outstanding Dissertation, University of Pennsylvania
  • 2015
    Rose Meadow Levinson Memorial Prize for medical student research, University of Pennsylvania

Selected Publications

  1. Kober KM, Chavez-Iglesias E, Cho NW, Yom S, Dixit N, Sirota M, Chan A, Olshen A. Consensus Co-Expression Analysis Identifies A Common Set Of Co-Expressed Genes Associated With Diabetic Peripheral Neuropathy And Chemotherapy-Induced Peripheral Neuropathy. bioRxiv. 2025 Nov 18;. doi: 10.1101/2025.11.18.689101. PubMed PMID: 41332704; PubMed Central PMCID: PMC12667829.
  2. Chavez-Iglesias E, Sucher A, Thati N, Trudeau J, Yom S, Sirota M, Olshen A, Cho NW, Kober KM. Alternative Splicing And Global Transcriptome Changes Associated With LPS Stimulation In Human Peripheral Blood Mononuclear Cells. bioRxiv. 2025 Nov 10;. doi: 10.1101/2025.11.09.687437. PubMed PMID: 41292868; PubMed Central PMCID: PMC12642489.
  3. Le C, Lewis M, Harris CS, Berger L, Chavez-Iglesias E, Morse L, Sucher A, Roy R, Olshen A, Hammer MJ, Paul S, Wallhagen M, Chan R, Sayer M, Yom S, Cho NW, Chan A, Levine J, Dhruva A, Miaskowski C, Conley YP, Kober KM. A Data-Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression-Associated Methylation. Cancer Med. 2025 Aug;14(15):e71067. doi: 10.1002/cam4.71067. PubMed PMID: 40709591; PubMed Central PMCID: PMC12290682.
  4. Nör C, Kharas K, Rasnitsyn A, Vladoiu MC, Cho NW, Young JS, Nör F, Mankahla N, Haapasalo J, Nordfors K, Rapic S, Skowron P, Suárez RA, Bahcheli AT, Ocsenas O, Chen X, Bahrampour S, Momin A, Sundaresan L, Ong W, Hendrikse LD, Abeysundara N, Juraschka K, Ly M, Pallota JG, Douglas T, Huang N, Wang H, Mak E, Qin L, Liu J, Shen L, Luu B, Manno A, Kumar SA, Donovan LK, Fong V, Richman C, Daniels C, Garzia L, Rich JN, Hawkins C, Wu X, DaCosta R, Reimand J, Huang X, Ramaswamy V, Raleigh DR, Taylor MD. Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process. Dev Cell. 2025 Nov 3;60(21):2880-2896.e7. doi: 10.1016/j.devcel.2025.06.016. Epub 2025 Jul 2. PubMed PMID: 40609543; NIHMSID:NIHMS2090341.
  5. Young JS, Cho NW, Lucas CG, Najem H, Mirchia K, Chen WC, Seo K, Zakimi N, Daggubati V, Casey-Clyde T, Nguyen MP, Chen A, Phillips JJ, Ozawa T, Aghi MK, Taylor JW, DeRisi JL, Bhaduri A, Berger MS, Heimberger AB, Butowski N, Spitzer MH, Raleigh DR. IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma. bioRxiv. 2025 Mar 14;. doi: 10.1101/2025.03.12.642800. PubMed PMID: 40161763; PubMed Central PMCID: PMC11952432.
  6. Mestrallet G, Brown M, Vaninov N, Cho NW, Velazquez L, Ananthanarayanan A, Spitzer M, Vabret N, Bozkus CC, Samstein RM, Bhardwaj N. Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer. bioRxiv. 2025 Feb 17;. doi: 10.1101/2025.02.12.637954. PubMed PMID: 40027748; PubMed Central PMCID: PMC11870396.
  7. Roschelle M, Rabbani R, Gweon S, Kumar R, Vercruysse A, Cho NW, Spitzer MH, Niknejad AM, Stojanović VM, Anwar M. A Wireless, Multicolor Fluorescence Image Sensor Implant for Real-Time Monitoring in Cancer Therapy. ArXiv. 2024 Jun 27;. PubMed PMID: 38979489; PubMed Central PMCID: PMC11230517.
  8. Liu SJ, Casey-Clyde T, Cho NW, Swinderman J, Pekmezci M, Dougherty MC, Foster K, Chen WC, Villanueva-Meyer JE, Swaney DL, Vasudevan HN, Choudhury A, Pak J, Breshears JD, Lang UE, Eaton CD, Hiam-Galvez KJ, Stevenson E, Chen KH, Lien BV, Wu D, Braunstein SE, Sneed PK, Magill ST, Lim D, McDermott MW, Berger MS, Perry A, Krogan NJ, Hansen MR, Spitzer MH, Gilbert L, Theodosopoulos PV, Raleigh DR. Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nat Commun. 2024 Jan 12;15(1):476. doi: 10.1038/s41467-023-40408-5. PubMed PMID: 38216587; PubMed Central PMCID: PMC10786948.
  9. Cho N, Raleigh D, Ziemer B, Nano T, Theodosopoulos P, Sneed P, Boreta L, Braunstein S, Ma L. Hypofractionated Brain Radiosurgery With Hundreds of Isocenters. International Journal of Radiation Oncology*Biology*Physics. 2021/11; 111(3, Supplement):e544-e545.
  10. Hiam-Galvez K, DeBarge R, Lareau C, Cho N, Yee J, Okholm T, Spitzer M. Transient dendritic cell activation diversifies the T cell response to acute infection. 2021/01; :2021.09.26.461821. doi: 10.1101/2021.09.26.461821.
  11. Cho N, Vasudevan H, Chan J, Chew J, Barcellos-Hoff M, Spitzer M, Yom S. Mass Cytometry for Comprehensive Profiling of Systemic Immune Composition in Head and Neck Squamous Cell Carcinoma Patients Reveals Dynamic Changes Early in Therapy. 2020/11; 108(3):e524-e525. doi: 10.1016/J.IJROBP.2020.07.1643.
  12. Allen BM, Hiam KJ, Burnett CE, Venida A, DeBarge R, Tenvooren I, Marquez DM, Cho NW, Carmi Y, Spitzer MH. Systemic dysfunction and plasticity of the immune macroenvironment in cancer models. Nat Med. 2020 Jul;26(7):1125-1134. doi: 10.1038/s41591-020-0892-6. Epub 2020 May 25. PubMed PMID: 32451499; PubMed Central PMCID: PMC7384250.
  13. Cho N, Descovich M, Yom S, Anwar M. Association of Treatment Characteristics and Clinical Outcomes for Hepatic Metastasis Re-irradiation Using Stereotactic Radiation. International Journal of Radiation Oncology, Biology, Physics. 2019; 105(1):E217. doi: 10.1016/j.ijrobp.2019.06.2065.
  14. Dilley RL, Verma P, Cho NW, Winters HD, Wondisford AR, Greenberg RA. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016 Nov 3;539(7627):54-58. doi: 10.1038/nature20099. Epub 2016 Oct 19. PubMed PMID: 27760120; PubMed Central PMCID: PMC5384111.
  15. Cho NW, Lampson MA, Greenberg RA. In vivo imaging of DNA double-strand break induced telomere mobility during alternative lengthening of telomeres. Methods. 2017 Feb 1;114:54-59. doi: 10.1016/j.ymeth.2016.07.010. Epub 2016 Aug 1. PubMed PMID: 27491801; PubMed Central PMCID: PMC5378164.
  16. Cho NW, Greenberg RA. DNA repair: Familiar ends with alternative endings. Nature. 2015 Feb 12;518(7538):174-6. doi: 10.1038/nature14200. Epub 2015 Feb 4. PubMed PMID: 25642961.
  17. Fishbein L, Khare S, Wubbenhorst B, DeSloover D, D'Andrea K, Merrill S, Cho NW, Greenberg RA, Else T, Montone K, LiVolsi V, Fraker D, Daber R, Cohen DL, Nathanson KL. Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Nat Commun. 2015 Jan 21;6:6140. doi: 10.1038/ncomms7140. PubMed PMID: 25608029; PubMed Central PMCID: PMC4302757.
  18. Cho NW, Dilley RL, Lampson MA, Greenberg RA. Interchromosomal homology searches drive directional ALT telomere movement and synapsis. Cell. 2014 Sep 25;159(1):108-121. doi: 10.1016/j.cell.2014.08.030. PubMed PMID: 25259924; PubMed Central PMCID: PMC4177039.
  19. Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, Mer G, Greenberg RA. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol. 2013 Mar;20(3):317-25. doi: 10.1038/nsmb.2499. Epub 2013 Feb 3. PubMed PMID: 23377543; PubMed Central PMCID: PMC3594358.
  20. Byun SJ, Choi KS, Park SH, Cho NW, Hyun Yoo C, Yun KJ, Koh YJ, Koh GY, So BJ, Yoon KH. Cartilage oligometric matrix protein-angiopoietin-1 promotes revascularization through increased survivin expression in dermal endothelial cells of skin grafts in mice. Am J Pathol. 2007 Nov;171(5):1682-90. doi: 10.2353/ajpath.2007.070142. Epub 2007 Sep 20. PubMed PMID: 17884969; PubMed Central PMCID: PMC2043528.

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