Education

Fellowship, 06/2018 - Molecular Genetic Pathology, University of California, San Francisco
Residency, 06/2008 - Anatomic Pathology, University of California, San Francisco
MD, 06/2006 - Medicine, Stanford Medical School
PhD, 06/2004 - Biochemistry, Stanford Medical School
BS/MS, 06/1996 - Biology and Music, Stanford University

Honors & Awards

  • 1998-1999
    Howard Hughes Medical Institute Medical Student Fellowship 
  • 1999-2002
    American Heart Association Predoctoral Fellowship, Stanford Medical School 
  • 2006-present
    Molecular Medicine Training Program, UCSF 
  • 2008-2011
    Clinical Fellow, California Institute for Regenerative Medicine, UCSF. 
  • 2007
    Chief Resident in Anatomic Pathology, San Francisco VA Medical Center 

Selected Publications

  1. Caliskan I, Mirchia K, Devine WP, Pekmezci M. TANC1::HTRA1 fusion in schwannomas. Brain Pathol. 2026 Feb 13; e70084. View on PubMed
  2. Kathiriya IS, Dominguez MH, Rao KS, Muncie-Vasic JM, Devine WP, Hu KM, Hota SK, Garay BI, Quintero D, Goyal P, Matthews MN, Thomas R, Sukonnik T, Miguel-Perez D, Winchester S, Brower EF, Forjaz A, Wu PH, Wirtz D, Kiemen AL, Bruneau BG. A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects. Nat Cardiovasc Res. 2026 Jan; 5(1):67-83. View on PubMed
  3. Gillespie WB, Zhang Y, Ruiz OE, Cerda J, Ortiz-Guzman J, Sherman M, Turner WD, Largoza G, Mosser LE, Fujimoto E, Chien CB, Kwan KM, Arenkiel BR, Devine WP, Wythe JD. MultiSite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox for use in vertebrate model systems. Development. 2025 Nov 15; 152(22). View on PubMed
  4. Tang V, Chou Y, Demirkesen C, Bloomer MM, Crawford JB, Sarici AM, Shields C, Eagle RC, Iacob CE, Devine WP, Milman T, Pekmezci M. Genomic Profiling of Intraocular Leiomyomas Reveals Recurrent Copy Number Alterations. Transl Vis Sci Technol. 2025 Nov 03; 14(11):25. View on PubMed
  5. Vargo SG, Rogerson D, Devine P, Van Ziffle J, Sparks TN. Insights Into Congenital Lymphatic Anomalies Underlying Fetal Effusions. Prenat Diagn. 2026 01; 46(1):3-11. View on PubMed
  6. Gulrajani NB, Lianoglou BR, Tick K, Sahin-Hodoglugil NN, Hodoglugil U, Devine P, Van Ziffle J, Norton ME, Sparks TN. Genetic diseases underlying a spectrum of fetal effusions. Am J Obstet Gynecol. 2025 Oct; 233(4):333.e1-333.e11. View on PubMed
  7. Gano D, Glenn OA, Rand L, Heraty K, Devine P, Norton ME, Sparks TN. Fetal Intracranial Hemorrhage due to Uniparental Disomy and Unmasked MPL-Related Congenital Amegakaryocytic Thrombocytopenia. Prenat Diagn. 2024 Dec 31. View on PubMed
  8. Xiao A, Shahmarvand N, Nagy A, Kumar J, Van Ziffle J, Devine P, Huang F, Lezama L, Li P, Ohgami RS. TFG::ALK fusion in ALK positive large B-cell lymphoma: a case report and review of literature. Front Oncol. 2023; 13:1174606. View on PubMed
  9. Tang V, Lu R, Mirchia K, Van Ziffle J, Devine P, Lee J, Phillips JJ, Perry A, Raleigh DR, Lucas CG, Solomon DA. Loss of p16 expression is a sensitive marker of CDKN2A homozygous deletion in malignant meningiomas. Acta Neuropathol. 2023 04; 145(4):497-500. View on PubMed
  10. Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, Hervey-Jumper SL, Gupta N, Oberheim Bush NA, Raleigh DR, Bollen A, Tihan T, Pekmezci M, Solomon DA, Phillips JJ, Perry A. Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma. J Neuropathol Exp Neurol. 2022 07 19; 81(8):650-657. View on PubMed
  11. Swanson K, Norton ME, Lianoglou BR, Jelin AC, Hodoglugil U, Van Ziffle J, Devine P, Sparks TN. The utility of pathologic examination and comprehensive phenotyping for accurate diagnosis with perinatal exome sequencing. Prenat Diagn. 2022 09; 42(10):1288-1294. View on PubMed
  12. Kortbawi H, Ames E, Pritchard A, Devine P, van Ziffle J, Slavotinek A. Further description of two patients with biallelic variants in NADSYN1 in association with cardiac and vertebral anomalies. Am J Med Genet A. 2022 08; 188(8):2479-2484. View on PubMed
  13. Natesan D, Zhang L, Martell HJ, Jindal T, Devine P, Stohr B, Espinosa-Mendez C, Grenert J, Van Ziffle J, Joseph N, Umetsu S, Onodera C, Turski M, Chan E, Desai A, Aggarwal R, Wong A, Porten S, Chou J, Friedlander T, Fong L, Small EJ, Sweet-Cordero A, Koshkin VS. APOBEC Mutational Signature and Tumor Mutational Burden as Predictors of Clinical Outcomes and Treatment Response in Patients With Advanced Urothelial Cancer. Front Oncol. 2022; 12:816706. View on PubMed
  14. Lucas CG, Abdullaev Z, Bruggers CS, Mirchia K, Whipple NS, Alashari MM, Lowichik A, Cheshier S, Phillips JJ, Devine P, Solomon DA, Quezado M, Aldape KD, Perry A. Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma. Acta Neuropathol. 2022 02; 143(2):283-286. View on PubMed
  15. Chenbhanich J, Hu Y, Hetts S, Cooke D, Dowd C, Devine P, UCLA Clinical Genomics Center, Russell B, Kang SHL, Chang VY, Abla AA, Cornett P, Yeh I, Lee H, Martinez-Agosto JA, Frieden IJ, Shieh JT. Segmental overgrowth and aneurysms due to mosaic PDGFRB p.(Tyr562Cys). Am J Med Genet A. 2021 05; 185(5):1430-1436. View on PubMed
  16. Klöckner C, Sticht H, Zacher P, Popp B, Babcock HE, Bakker DP, Barwick K, Bonfert MV, Bönnemann CG, Brilstra EH, Care4Rare Canada Consortium, Chung WK, Clarke AJ, Devine P, Donkervoort S, Fraser JL, Friedman J, Gates A, Ghoumid J, Hobson E, Horvath G, Keller-Ramey J, Keren B, Kurian MA, Lee V, Leppig KA, Lundgren J, McDonald MT, McLaughlin HM, McTague A, Mefford HC, Mignot C, Mikati MA, Nava C, Raymond FL, Sampson JR, Sanchis-Juan A, Shashi V, Shieh JTC, Shinawi M, Slavotinek A, Stödberg T, Stong N, Sullivan JA, Taylor AC, Toler TL, van den Boogaard MJ, van der Crabben SN, van Gassen KLI, van Jaarsveld RH, Van Ziffle J, Wadley AF, Wagner M, Wigby K, Wortmann SB, Zarate YA, Møller RS, Lemke JR, Platzer K. De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy. Genet Med. 2021 04; 23(4):653-660. View on PubMed
  17. Sparks TN, Lianoglou BR, Adami RR, Pluym ID, Holliman K, Duffy J, Downum SL, Patel S, Faubel A, Boe NM, Field NT, Murphy A, Laurent LC, Jolley J, Uy C, Slavotinek AM, Devine P, Hodoglugil U, Van Ziffle J, Sanders SJ, MacKenzie TC, Norton ME, University of California Fetal–Maternal Consortium, University of California, San Francisco Center for Maternal–Fetal Precision Medicine. Exome Sequencing for Prenatal Diagnosis in Nonimmune Hydrops Fetalis. N Engl J Med. 2020 10 29; 383(18):1746-1756. View on PubMed
  18. Rabban JT, Devine WP, Sangoi AR, Poder L, Alvarez E, Davis JL, Rudzinski E, Garg K, Bean GR. NTRK fusion cervical sarcoma: a report of three cases, emphasising morphological and immunohistochemical distinction from other uterine sarcomas, including adenosarcoma. Histopathology. 2020 Jul; 77(1):100-111. View on PubMed
  19. Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, Metrock LK, Jin LW, Antony R, Alashari M, Cheshier S, Whipple NS, Bruggers C, Raffel C, Gupta N, Kline CN, Reddy A, Banerjee A, Hall MD, Mehta MP, Khatib Z, Maher OM, Brathwaite C, Pekmezci M, Phillips JJ, Bollen AW, Tihan T, Lucas JT, Broniscer A, Berger MS, Perry A, Orr BA, Solomon DA. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathol. 2020 06; 139(6):1071-1088. View on PubMed
  20. Pfeil J, Sanders LM, Anastopoulos I, Lyle AG, Weinstein AS, Xue Y, Blair A, Beale HC, Lee A, Leung SG, Dinh PT, Shah AT, Breese MR, Devine WP, Bjork I, Salama SR, Sweet-Cordero EA, Haussler D, Vaske OM. Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures. PLoS Comput Biol. 2020 04; 16(4):e1007753. View on PubMed

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