Research Funding

  • January 3, 2019 - January 4, 2026 - Mitigating long-term treatment-related morbidity in Childhood Cancer Survivors, Co-Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R35CA220502 01A1
  • December 1, 2019 - November 30, 2022 - Utilizing animal models to investigate therapy-induced malignancies, Co-Investigator. Sponsor: , Sponsor Award ID: John Templeton Foundation
  • September 1, 2015 - August 31, 2020 - Developmental and HyperActive Ras Tumor SPORE, Co-Investigator. Sponsor: NIH/NCI, Sponsor Award ID: U54CA196519
  • August 2, 2018 - August 1, 2020 - Metabolic vulnerabilities of NF1 mutant tumors, PI. Sponsor: Department of Defense, Sponsor Award ID: NF170039

Education

University of Chicago, Chicago, Illinois, A.B., 1993, Biological Sciences
University of Chicago, Chicago, Illinois, M.D., 1998, Medicine
University of Chicago, Chicago, Illinois, Internship, 1999, Internal Medicine
University of California, San Francisco, Postdoctorate, 2002, Neuro-Oncology
University of California, San Francisco, Residency, 2003, Radiation Oncology

Honors & Awards

  • 1990
    Illinois State Scholar
  • 1990
    National Merit Scholarship
  • 1993
    Graduated with General Honors from The University of Chicago College in the Biological Sciences
  • 1995
    Student Summer Research Award, University of Chicago, Pritzker School of Medicine
  • 1998
    Catherine Dobson Prize for Best Oral Presentation given at 52nd Annual Senior Scientific Session by a Non-PhD Student in the Area of Clinical Investigation Research done in Medical School
  • 1998
    University of Chicago Departmental Award for Outstanding Performance in the General Field of Radiation Oncology
  • 2001
    Radiological Society of North America Roentgen Award for Resident Research for the paper, "Dose conformity of gamma knife radiosurgery and risk factors for complications"
  • 2002
    Radiological Society of North America Roentgen Award for Resident Research for the paper, "Inhibition of PI3 kinase causes cell death through a PKB dependent mechanism and growth arrest through a PKB independent mechanism"
  • 2002
    American Brain Tumor Association Basic Research Fellowship Award
  • 2004
    American Society for Therapeutic Radiology and Oncology Basic Science Travel Grant to the 46th Annual Meeting in Atlanta, GA
  • 2008
    Irene Holmes Perstein Award, UCSF

Selected Publications

  1. Park I, Kim S, Pucciarelli D, Song J, Choi JM, Lee KH, Kim YH, Jung S, Yoon W, Nakamura JL Differentiating Radiation Necrosis from Brain Tumor Using Hyperpolarized Carbon-13 MR Metabolic Imaging.  View on PubMed
  2. Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection.  View on PubMed
  3. Lavergne V, Sabnis A, Tupule A, Davidson PR, Kline C, Matthay K, Nicolaides T, Goldsby R, Braunstein S, Fogh SE, Sneed PK, Menzel P, Nakamura A, DuBois SG, Haas-Kogan DA, Nakamura JL Germline MUTYH Mutation in a Pediatric Cancer Survivor Developing a Secondary Malignancy.  View on PubMed
  4. Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K Defining the ATPome reveals cross-optimization of metabolic pathways.  View on PubMed
  5. Pucciarelli D, Angus SP, Huang B, Zhang C, Nakaoka HJ, Krishnamurthi G, Bandyopadhyay S, Clapp DW, Shannon K, Johnson GL, Nakamura JL Nf1-Mutant Tumors Undergo Transcriptome and Kinome Remodeling after Inhibition of either mTOR or MEK.  View on PubMed
  6. Susko MS, Garcia MA, Ma L, Nakamura JL, Raleigh DR, Fogh S, Theodosopoulos P, McDermott M, Sneed PK, Braunstein SE Stereotactic Radiosurgery to More Than 10 Brain Metastases: Evidence to Support the Role of Radiosurgery for Ideal Hippocampal Sparing in the Treatment of Multiple Brain Metastases.  View on PubMed
  7. Bhatia S, Chen Y, Wong FL, Hageman L, Smith K, Korf B, Cannon A, Leidy DJ, Paz A, Andress JE, Friedman GK, Metrock K, Neglia JP, Arnold M, Turcotte LM, de Blank P, Leisenring W, Armstrong GT, Robison LL, Clapp DW, Shannon K, Nakamura JL, Fisher MJ Subsequent Neoplasms After a Primary Tumor in Individuals With Neurofibromatosis Type 1.  View on PubMed
  8. Chapman CH, Hara JH, Molinaro AM, Clarke JL, Oberheim Bush NA, Taylor JW, Butowski NA, Chang SM, Fogh SE, Sneed PK, Nakamura JL, Raleigh DR, Braunstein SE Reirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival.  View on PubMed
  9. Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.  View on PubMed
  10. Garcia MA, Anwar M, Yu Y, Duriseti S, Merritt B, Nakamura J, Hess C, Theodosopoulos PV, McDermott M, Sneed PK, Braunstein SE Brain metastasis growth on preradiosurgical magnetic resonance imaging.  View on PubMed
  11. Ojha J, Dyagil I, Finch SC, Reiss RF, de Smith AJ, Gonseth S, Zhou M, Hansen HM, Sherborne AL, Nakamura J, Bracci PM, Gudzenko N, Hatch M, Babkina N, Little MP, Chumak VV, Walsh KM, Bazyka D, Wiemels JL, Zablotska LB Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers.  View on PubMed
  12. Thibodeau BJ, Lavergne V, Dekhne N, Benitez P, Amin M, Ahmed S, Nakamura JL, Davidson PR, Nakamura AO, Grills IS, Chen PY, Wobb J, Wilson GD Mutational landscape of radiation-associated angiosarcoma of the breast.  View on PubMed
  13. Davidson PR, Sherborne AL, Taylor B, Nakamura AO, Nakamura JL A pooled mutational analysis identifies ionizing radiation-associated mutational signatures conserved between mouse and human malignancies.  View on PubMed
  14. Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience.  View on PubMed
  15. Sherborne AL, Lavergne V, Yu K, Lee L, Davidson PR, Mazor T, Smirnoff IV, Horvai AE, Loh M, DuBois SG, Goldsby RE, Neglia JP, Hammond S, Robison LL, Wustrack R, Costello JF, Nakamura AO, Shannon KM, Bhatia S, Nakamura JL Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors.  View on PubMed
  16. Garcia MA, Lazar A, Duriseti S, Raleigh DR, Hess CP, Fogh SE, Barani IJ, Nakamura JL, Larson DA, Theodosopoulos P, McDermott M, Sneed PK, Braunstein S Discovery of additional brain metastases on the day of stereotactic radiosurgery: risk factors and outcomes.  View on PubMed
  17. Kaprealian T, Raleigh DR, Sneed PK, Nabavizadeh N, Nakamura JL, McDermott MW Parameters influencing local control of meningiomas treated with radiosurgery.  View on PubMed
  18. Held M, Cremers F, Sneed PK, Braunstein S, Fogh SE, Nakamura J, Barani I, Perez-Andujar A, Pouliot J, Morin O Assessment of image quality and dose calculation accuracy on kV CBCT, MV CBCT, and MV CT images for urgent palliative radiotherapy treatments.  View on PubMed
  19. McGuinness CM, Gottschalk AR, Lessard E, Nakamura JL, Pinnaduwage D, Pouliot J, Sims C, Descovich M Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients.  View on PubMed
  20. Sherborne AL, Davidson PR, Yu K, Nakamura AO, Rashid M, Nakamura JL Mutational Analysis of Ionizing Radiation Induced Neoplasms.  View on PubMed

Go to UCSF Profiles, powered by CTSI