University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Steven Hetts, MD

Steven Hetts, MD

Associate Professor in Residence of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Pediatric Malignancies

Research Summary

Steven Hetts, MD, is an Associate Professor of Radiology in Residence at the University of California, San Francisco, and he is Chief of Neuroradiology at the San Francisco General Hospital where he has established a new clinical Interventional Neuroradiology service, providing cutting edge minimally invasive endovascular therapy. Dr. Hetts received his medical degree from Harvard Medical School in Boston, Massachusetts in 2000, and completed a residency in Diagnostic Radiology at UCSF, followed by a fellowship in Diagnostic Neuroradiology and Interventional Neuroradiology from UCSF.

Dr. Hetts is involved in translational research as Co-Director of the Interventional Radiology Laboratory at China Basin, including the conception, performance, and management of research projects translating basic science and engineering research into clinical applicability. One of his projects is Magnetic Catheter Navigation and Microinfarction Evaluation in the Brain and Heart. Dr. Hetts also implements many clinical research projects involving retrospective and prospective patient data. The main focus of his clinical research is endovascular therapy for cerebrovascular disease, spinal vascular disease, and neurooncology.

Education

Harvard College, Boston, MA, AB summa cum laude, 06/1996, Biology
Harvard Medical School, Boston, MA, MD, 06/2000, Medicine
Stanford University Medical Center, Stanford, CA, Internship, 06/2001, Internal Medicine
UCSF Medical Center, San Francisco, CA, Residency, 06/2005, Diagnostic Radiology
UCSF Medical Center, San Francisco, CA, Fellowship, 06/2006, Diagnostic Neuroradiology
UCSF Medical Center, San Francisco, CA, Fellowship, 02/2008, Interventional Neuroradiology


Professional Experience

  • 1991-1992
    Research Associate, Department of Cell Genetics, Genentech, Inc., South San Francisco, CA
  • 1993
    Research Associate, UCSF Department of Radiology
  • 1993
    Research Associate, UCSF Center for Medical Technology Assessment
  • 1994
    Research Associate, The Parkinson’s Institute, Sunnyvale, CA
  • 1994-1996
    Research Associate, Department of Neurology, Children’s Hospital, Boston, MA
  • 1997
    Research Associate, Department of Biology, Tularik, Inc., South San Francisco, CA
  • 2000-2001
    Intern Physician in Internal Medicine, Stanford University Hospital
  • 2001-2005
    Resident Physician in Diagnostic Radiology, UCSF Medical Center
  • 2003-2007
    Co-Investigator, NIH R01 HL076486 (Wilson), UCSF Medical Center 
  • 2005-2006
    Clinical Fellow in Diagnostic Neuroradiology, UCSF Medical Center
  • 2006-2008
    Clinical Fellow in Interventional Neuroradiology, UCSF Medical Center
  • 2008-2013
    Assistant Professor in Residence, Radiology, UCSF
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco General Hospital
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco VA Medical Center
  • 2008-current
    Attending Interventional Neuroradiologist, UCSF Medical Center
  • 2009-current
    Co-Director, UCSF/SFGH Interventional Radiology Research Laboratory
  • 2009-2010
    Co-Director, Neurovascular/Neurointerventional Research Interest Group, UCSF Radiology
  • 2010-current
    Co-Director, Image-Guided Therapy Specialized Resource Group, UCSF Radiology
  • 2013-current
    Chief Medical Officer and Co-Founder, ChemoFilter, Inc., Hillsborough, CA
  • 2013-current
    Associate Professor in Residence, Radiology, UCSF 
  • 2014-current
    Co-Director, UCSF Hereditary Hemorrhagic Telangiectasia Center of Excellence
  • 2015-current
    Chief of Interventional Neuroradiology, UCSF Benioff Children’s Hospital, UCSF Betty Irene Moore Women’s Hospital, and UCSF Bakar Cancer Hospital

Honors & Awards

  • 1992
    United States Presidential Scholar, highest academic honor for US high school students
  • 1993-1996
    John Harvard Scholarship and Dean’s List, Harvard College
  • 1995
    Phi Beta Kappa, elected in Senior 45, Harvard College
  • 1996
    Biology Undergraduate Honors Thesis, summa cum laude
  • 1997
    Finalist, Rhodes Scholarship, California Nominee to Region VIII Competition
  • 1999
    Aesculapian Club, Harvard Medical School
  • 2001
    Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital
  • 2002, 2003
    Margulis Society Radiology Resident Research Award
  • 2003
    American Roentgen Ray Society Introduction to Research Program
  • 2004
    International Society for Magnetic Resonance in Medicine Amersham Fellowship
  • 2004
    American Society of Pediatric Neuroradiology Annual Research Award
  • 2005
    Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society
  • 2010, 2011
    American Society of Neuroradiology, Neuroradiology Research and Education Foundation Scholar Award in Neuroradiology Research
  • 2012
    Visiting Professor, Memorial Sloan Kettering Cancer Center
  • 2015
    Nominee, QB3 Award for Startup of the Year, ChemoFilter
  • 2015
    Fellow, Rosenman Institute, UCSF

Selected Publications

  1. Fox CK, Fullerton HJ, Hetts SW, Halbach VV, Auguste KI, Lawton MT, Gupta N. Single center series of boys with recurrent strokes and rotational vertebral arteriopathy. Neurology. 2020 Jul 20.
    View on PubMed
  2. Zaidat OO, Hanel RA, Sauvageau EA, Aghaebrahim A, Lin E, Jadhav AP, Jovin TG, Khaldi A, Gupta RG, Johnson A, Frei D, Loy D, Malek A, Toth G, Siddiqui A, Reavey-Cantwell J, Thomas A, Hetts SW, Jankowitz BT. Pivotal Trial of the Neuroform Atlas Stent for Treatment of Anterior Circulation Aneurysms: One-Year Outcomes. Stroke. 2020 Jul; 51(7):2087-2094.
    View on PubMed
  3. Vella M, Alexander MD, Mabray MC, Cooke DL, Amans MR, Glastonbury CM, Kim H, Wilson MW, Langston DE, Conrad MB, Hetts SW. Comparison of MRI, MRA, and DSA for Detection of Cerebral Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. AJNR Am J Neuroradiol. 2020 Jun; 41(6):969-975.
    View on PubMed
  4. Raper DMS, Winkler EA, Rutledge WC, Hetts SW, Abla AA. Interhemispheric Surgical Approaches for Ruptured Intraventricular Arteriovenous Malformation-Associated Aneurysms: Technical Report and Case Series. World Neurosurg. 2020 Apr 25.
    View on PubMed
  5. Winkler EA, Lu A, Morshed RA, Yue JK, Rutledge WC, Burkhardt JK, Patel AB, Ammanuel SG, Braunstein S, Fox CK, Fullerton HJ, Kim H, Cooke D, Hetts SW, Lawton MT, Abla AA, Gupta N. Bringing high-grade arteriovenous malformations under control: clinical outcomes following multimodality treatment in children. J Neurosurg Pediatr. 2020 Apr 10; 1-10.
    View on PubMed
  6. Morshed RA, Winkler EA, Kim H, Braunstein S, Cooke DL, Hetts SW, Abla AA, Fullerton HJ, Gupta N. High-Flow Vascular Malformations in Children. Semin Neurol. 2020 Jun; 40(3):303-314.
    View on PubMed
  7. Maani N, Diorio TC, Hetts SW, Rayz VL. Computational modeling of drug transport and mixing in the chemofilter device: enhancing the removal of chemotherapeutics from circulation. Biomech Model Mechanobiol. 2020 Mar 12.
    View on PubMed
  8. Knox JA, Alexander MD, McCoy DB, Murph DC, Hinckley PJ, Ch'ang JC, Dowd CF, Halbach VV, Higashida RT, Amans MR, Hetts SW, Cooke DL. Impact of Aortic Arch Anatomy on Technical Performance and Clinical Outcomes in Patients with Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2020 02; 41(2):268-273.
    View on PubMed
  9. Liu X, Vitt JR, Hetts SW, Gudelunas K, Ho N, Ko N, Hu X. Morphological changes of intracranial pressure quantifies vasodilatory effect of verapamil to treat cerebral vasospasm. J Neurointerv Surg. 2020 Jan 20.
    View on PubMed
  10. Srinivasan VM, Srivatsan A, Spiotta AM, Hendricks BK, Ducruet AF, Albuquerque FC, Puri A, Amans MR, Hetts SW, Cooke DL, Ogilvy CS, Thomas AJ, Enriquez-Marulanda A, Rai A, Boo S, Carlson AP, Crowley RW, Rangel-Castilla L, Lanzino G, Chen PR, Diaz O, Bohnstedt BN, O'Connor KP, Burkhardt JK, Johnson JN, Chen SR, Kan P. Early postmarket results with PulseRider for treatment of wide-necked intracranial aneurysms: a multicenter experience. J Neurosurg. 2019 Nov 08; 1-10.
    View on PubMed
  11. Hetts S, Khangura R. Imaging of Acute Stroke: Current State. Radiol Clin North Am. 2019 Nov; 57(6):1083-1091.
    View on PubMed
  12. Yee C, McCoy D, Yu J, Losey A, Jordan C, Moore T, Stillson C, Oh HJ, Kilbride B, Roy S, Patel A, Wilson MW, Hetts SW. Endovascular Ion Exchange Chemofiltration Device Reduces Off-Target Doxorubicin Exposure in a Hepatic Intra-arterial Chemotherapy Model. Radiol Imaging Cancer. 2019 Sep 27; 1(1):e190009.
    View on PubMed
  13. Rehani B, Ammanuel SG, Zhang Y, Smith W, Cooke DL, Hetts SW, Josephson SA, Kim A, Hemphill JC, Dillon W. A New Era of Extended Time Window Acute Stroke Interventions Guided by Imaging. Neurohospitalist. 2020 Jan; 10(1):29-37.
    View on PubMed
  14. Alexander MD, Halbach VV, Hallam DK, Cooke DL, Ghodke BV, Dowd CF, Amans MR, Hetts SW, Higashida RT, Meyers PM. Long-Term Outcomes of Endovascular Treatment of Indirect Carotid Cavernous Fistulae: Superior Efficacy, Safety, and Durability of Transvenous Coiling Over Other Techniques. Neurosurgery. 2019 07 01; 85(1):E94-E100.
    View on PubMed
  15. Jordan CD, Thorne BRH, Wadhwa A, Losey AD, Ozhinsky E, Kondapavulur S, Fratello V, Moore T, Stillson C, Yee C, Watkins RD, Scott GC, Martin AJ, Zhang X, Wilson MW, Hetts SW. Wireless Resonant Circuits Printed Using Aerosol Jet Deposition for MRI Catheter Tracking. IEEE Trans Biomed Eng. 2020 03; 67(3):876-882.
    View on PubMed
  16. Donzelli GF, Nelson J, McCoy D, McCulloch CE, Hetts SW, Amans MR, Dowd CF, Halbach VV, Higashida RT, Lawton MT, Kim H, Cooke DL. The effect of preoperative embolization and flow dynamics on resection of brain arteriovenous malformations. J Neurosurg. 2019 May 17; 1-9.
    View on PubMed
  17. Rutledge C, Jonzzon S, Winkler EA, Hetts SW, Abla AA. Transcortical transventricular transchoroidal-fissure approach to distal fusiform hyperplastic anterior choroidal artery aneurysms. Br J Neurosurg. 2019 04 22; 1-5.
    View on PubMed
  18. Hetts SW. Diving into a Shallow Pool: Endovascular Treatment for Basilar Artery Occlusion. Radiology. 2019 Jun; 291(3):738-739.
    View on PubMed
  19. Alexander MD, Halbach VV, Hallam DK, Cooke DL, Ghodke B, Dowd CF, Amans MR, Hetts SW, Higashida RT, Meyers PM. Relationship of clinical presentation and angiographic findings in patients with indirect cavernous carotid fistulae. J Neurointerv Surg. 2019 Sep; 11(9):937-939.
    View on PubMed
  20. Liu X, Gadhoumi K, Xiao R, Tran N, Smielewski P, Czosnyka M, Hetts SW, Ko N, Hu X. Continuous monitoring of cerebrovascular reactivity through pulse transit time and intracranial pressure. Physiol Meas. 2019 01 23; 40(1):01LT01.
    View on PubMed

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