University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Sue S. Yom, MD, PhD

Sue S. Yom, MD, PhD

Professor, Department of Radiation Oncology, UCSF

Cancer Center Program Memberships

Experimental Therapeutics

Research Summary

My primary clinical and research interests include head and neck, thoracic, and cutaneous malignancies, where I have developed and led multiple clinical trials, both within UCSF and across sites nationwide and overseas. I am interested in the development and evaluation of new therapeutic techniques, which to me include novel molecular targeted agents and immunotherapies as well as state-of-the-art technical advances in radiation therapy. I have special interests in virally driven malignancies associated with humanpapillomavirus (HPV), Epstein-Barr virus (EBV), and Merkel cell polyomavirus. My research has entailed collaborating with laboratory-based investigators to identify patient, tumor, and technical characteristics that influence prognosis and response to specific therapies, including tissue-, blood-, and imaging-based biomarkers. Other university responsibilities include co-leading the site committees for clinical trial development in cutaneous and head and neck cancers at the UCSF HDFCCC and serving on the Cancer Committee which maintains our accreditation through the American College of Surgeons. Nationally, I have served as the chair of the scientific program and nominating committees for the American Radium Society (ARS), chair of the Appropriateness Committee guidelines for radiation oncology at the American College of Radiology (ACR), and head and neck senior editor at the International Journal for Radiation Oncology Biology Physics (IJROBP). I have been on the scientific program committees of the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC), and the American Head and Neck Society (AHNS). I am a member of the NRG Oncology Head and Neck Steering Committee, NCI’s Head and Neck Recurrent/Metastatic Disease Task Force, and the NCCN Head and Neck Cancers guidelines committee. I am a national boards examiner for the American Board of Radiology.

Education

2002, University of Pennsylvania, Philadelphia, PA, M.D., Ph.D., Medicine/English
2003, U. T. – M. D. Anderson Cancer Center, Internship, Medicine/Surgery
2007, U. T. – M. D. Anderson Cancer Center, Residency, Radiation Oncology


Professional Experience

  • 2007-2013
    Assistant Professor of Clinical Radiation Oncology, University of California, San Francisco
  • 2007-present
    Consultant in Radiology, San Francisco Veterans Administration Medical Center
  • 2008-2013
    Assistant Professor in Otolaryngology-Head and Neck Surgery, by courtesy
  • 2013-present
    Professor of Clinical Radiation Oncology, University of California, San Francisco
  • 2013-present
    Professor in Otolaryngology-Head and Neck Surgery, by courtesy

Honors & Awards

  • 1992
    Mellon Fellow in the Humanities, Andrew W. Mellon Foundation
  • 1995
    Benjamin Franklin Medical Scholar Fellowship, University of Pennsylvania
  • 2004
    Thomas Barkley Award, M. D. Anderson Cancer Center
  • 2005
    Fellowship, Korean American Society for Therapeutic Radiology & Oncology
  • 2006
    Jesse H. Jones Fellowship in Cancer Education, M. D. Anderson Cancer Center
  • 2006
    Outstanding Resident Presentation Award, Texas Radiological Society
  • 2006
    A. Lavoy Moore Endowment Fund, M. D. Anderson Cancer Center
  • 2006
    Eleanor Montague Distinguished Resident Award, American Association of Women Radiologists
  • 2008
    Joan F. Giambalvo Memorial Scholarship, AMA Women Physicians Congress
  • 2009
    Best Doctors in America, 2009-2014
  • 2011
    Educator of the Year Award, Association of Residents in Radiation Oncology

Selected Publications

  1. Hohenstein NA, Chan JW, Wu SY, Tahir P, Yom SS. Diagnosis, Staging, Radiation Treatment Response Assessment, and Outcome Prognostication of Head and Neck Cancers Using PET Imaging: A Systematic Review. PET Clin. 2020 Jan; 15(1):65-75.
    View on PubMed
  2. McDowell L, Yom SS. Locally advanced non-melanomatous skin cancer: Contemporary radiotherapeutic management. Oral Oncol. 2019 Nov 22; 99:104443.
    View on PubMed
  3. Zietman AL, Yom SS. Statement From the Editors. Int J Radiat Oncol Biol Phys. 2019 Nov 15; 105(4):905.
    View on PubMed
  4. Tegbaru D, Braverman L, Zietman AL, Yom SS, Lee WR, Miller RC, Jackson IL, McNutt T, Dekker A. ASTRO Journals' Data Sharing Policy and Recommended Best Practices. Adv Radiat Oncol. 2019 Oct-Dec; 4(4):551-558.
    View on PubMed
  5. Eldridge RC, Pugh SL, Trotti A, Hu K, Spencer S, Yom SS, Rosenthal D, Read N, Desai A, Gore E, Shenouda G, Mishra MV, Bruner D, Xiao C. Changing functional status within 6 months posttreatment is prognostic of overall survival in patients with head and neck cancer: NRG Oncology Study. Head Neck. 2019 Nov; 41(11):3924-3932.
    View on PubMed
  6. Lee AWM, Ng WT, Chan JYW, Corry J, Mäkitie A, Mendenhall WM, Rinaldo A, Rodrigo JP, Saba NF, Strojan P, Suárez C, Vermorken JB, Yom SS, Ferlito A. Management of locally recurrent nasopharyngeal carcinoma. Cancer Treat Rev. 2019 Sep; 79:101890.
    View on PubMed
  7. Mell LK, Shen H, Nguyen-Tân PF, Rosenthal DI, Zakeri K, Vitzthum LK, Frank SJ, Schiff PB, Trotti AM, Bonner JA, Jones CU, Yom SS, Thorstad WL, Wong SJ, Shenouda G, Ridge JA, Zhang QE, Le QT. Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer. Clin Cancer Res. 2019 Aug 16.
    View on PubMed
  8. Kearney V, Chan JW, Wang T, Perry A, Yom SS, Solberg TD. Attention-enabled 3D boosted convolutional neural networks for semantic CT segmentation using deep supervision. Phys Med Biol. 2019 Jul 02; 64(13):135001.
    View on PubMed
  9. Lee AW, Ng WT, Pan JJ, Chiang CL, Poh SS, Choi HC, Ahn YC, AlHussain H, Corry J, Grau C, Grégoire V, Harrington KJ, Hu CS, Kwong DL, Langendijk JA, Le QT, Lee NY, Lin JC, Lu TX, Mendenhall WM, O'Sullivan B, Ozyar E, Peters LJ, Rosenthal DI, Sanguineti G, Soong YL, Tao Y, Yom SS, Wee JT. International Guideline on Dose Prioritization and Acceptance Criteria in Radiation Therapy Planning for Nasopharyngeal Carcinoma. Int J Radiat Oncol Biol Phys. 2019 Nov 01; 105(3):567-580.
    View on PubMed
  10. Braverman LC, Yom SS, Zietman AL. Think Carefully, Publish Safely: Co-Authorship and Conflict of Interest Verification in the ASTRO Journals. Int J Radiat Oncol Biol Phys. 2019 Jul 01; 104(3):486-487.
    View on PubMed
  11. Strohl MP, Chen JP, Ha PK, Seth R, Yom SS, Heaton CM. Can Early Dental Extractions Reduce Delays in Postoperative Radiation for Patients With Advanced Oral Cavity Carcinoma? J Oral Maxillofac Surg. 2019 May 25.
    View on PubMed
  12. Kallianos KG, Muhoozi BN, Gottschalk A, Yom SS, Chan JW, Henry TS, Elicker BM, Ordovas KG, Naeger DM. Dedicated Diagnostic Radiology/Radiation Oncology Rounds: Added Value Beyond Traditional Tumor Boards. Curr Probl Diagn Radiol. 2019 May 09.
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  13. Zietman AL, Yom SS. The Red Journal's Outstanding Reviewers of 2018. Int J Radiat Oncol Biol Phys. 2019 Jul 15; 104(4):703-704.
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  14. de Groot PM, Chung JH, Ackman JB, Berry MF, Carter BW, Colletti PM, Hobbs SB, McComb BL, Movsas B, Tong BC, Walker CM, Yom SS, Kanne JP. ACR Appropriateness Criteria® Noninvasive Clinical Staging of Primary Lung Cancer. J Am Coll Radiol. 2019 May; 16(5S):S184-S195.
    View on PubMed
  15. Gay HA, Santiago R, Gil B, Remedios C, Montes PJ, López-Araujo J, Chévere CM, Imbert WS, White J, Arthur DW, Horton JK, Jagsi R, Rabinovich R, Beriwal S, Viswanathan A, Erickson BA, Rengan R, Palma D, Loo BW, Kavanaugh JA, Bradley J, Yom SS, Harari PM, Lee Burnett O. Lessons Learned From Hurricane Maria in Puerto Rico: Practical Measures to Mitigate the Impact of a Catastrophic Natural Disaster on Radiation Oncology Patients. Pract Radiat Oncol. 2019 Sep - Oct; 9(5):305-321.
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  16. Chan JW, Kearney V, Haaf S, Wu S, Bogdanov M, Reddick M, Dixit N, Sudhyadhom A, Chen J, Yom SS, Solberg TD. A convolutional neural network algorithm for automatic segmentation of head and neck organs at risk using deep lifelong learning. Med Phys. 2019 May; 46(5):2204-2213.
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  17. Sun L, Chin RI, Gastman B, Thorstad W, Yom SS, Reddy CA, Nussenbaum B, Wang SJ, Knackstedt T, Vidimos AT, Koyfman SA, Manyam BV. Association of Disease Recurrence With Survival Outcomes in Patients With Cutaneous Squamous Cell Carcinoma of the Head and Neck Treated With Multimodality Therapy. JAMA Dermatol. 2019 Apr 01; 155(4):442-447.
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  18. Yom SS. Integrating the Management of Nodal Metastasis Into the Treatment of Nonmelanoma Skin Cancer. Semin Radiat Oncol. 2019 04; 29(2):171-179.
    View on PubMed
  19. Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR. Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer. Laryngoscope. 2019 Mar 27.
    View on PubMed
  20. Fakhry C, Zhang Q, Gillison ML, Nguyen-Tân PF, Rosenthal DI, Weber RS, Lambert L, Trotti AM, Barrett WL, Thorstad WL, Yom SS, Wong SJ, Ridge JA, Rao SSD, Spencer S, Fortin A, Raben D, Harris J, Le QT. Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials. Cancer. 2019 Jun 15; 125(12):2027-2038.
    View on PubMed

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