I am a physician-scientist whose research program focuses on hematopoietic growth control, genetic mechanisms underlying leukemogenesis, aberrant Ras signaling in human developmental disorders and cancer, mouse cancer modeling, and molecular therapeutics. I served as Director of the UCSF Medical Scientist Training Program (MSTP) from 2006-2012. I have been a research mentor for medical students, graduate students, and post-doctoral scholars, including six post-doctoral scholars who received “K” series awards from the NCI.
September 1, 2015 - August 31, 2026 - Developmental and HyperActive Ras Tumor SPORE , Multiple Principal Investigator . Sponsor: NIH, Sponsor Award ID: U54CA196519
April 1, 2015 - March 31, 2026 - Selectively Targeting Oncogenic NRAS in Cancer , Principal Investigtor . Sponsor: NIH, Sponsor Award ID: R01CA193994
February 15, 2022 - February 14, 2024 - Co-targeting Raf and MEK in Pediatric Acute Myeloid Leukemia , Principal Investigator . Sponsor: Cookies for Kids Cancer Foundation, Sponsor Award ID: Research Graant
Williams College, Williamstown, MA, A.B., 1976, Biology, Liberal Arts
Cornell University, New York, NY, M.D., 1979, Medicine
University of Texas Southwestern, Dallas, TX, Resident, 1982, Pediatrics
University of California, San Francisco (UCSF), Postdoctoral, 1988, Hematology/Oncology