Research Summary
I am a physician-scientist whose research program focuses on hematopoietic growth control, genetic mechanisms underlying leukemogenesis, aberrant Ras signaling in human developmental disorders and cancer, mouse cancer modeling, and molecular therapeutics. I served as Director of the UCSF Medical Scientist Training Program (MSTP) from 2006-2012. I have been a research mentor for medical students, graduate students, and post-doctoral scholars, including six post-doctoral scholars who received “K” series awards from the NCI.
Research Funding
July 1, 2019 - June 30, 2022 - Co-targeting BET Bromodomain Proteins and Aberrant Ras Signaling in Signaling in Pediatric AML, Principal Investigator. Sponsor: Leukemia and Lymphoma Society, Sponsor Award ID: LLS TRP Award
May 22, 2017 - April 30, 2022 - In Vivo Functional Analysis of Chromosome 7q22 Deletions in Myeloid Malignancies, Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA216352
July 1, 1978 - June 30, 2021 - Medical Scientist Training Program, Co-Principal Investigator. Sponsor: NIH/NIGMS, Sponsor Award ID: T32GM007618
September 1, 2015 - August 31, 2020 - Developmental and HyperActive Ras Tumor SPORE, Multiple Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: U54CA196519
Education
Williams College, Williamstown, MA, A.B., 1976, Biology, Liberal Arts
Cornell University, New York, NY, M.D., 1979, Medicine
University of Texas Southwestern, Dallas, TX, Resident, 1982, Pediatrics
University of California, San Francisco (UCSF), Postdoctoral, 1988, Hematology/Oncology