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Small Molecule Discovery Core combines high-throughput biology and medicinal chemistry to accelerate drug discovery
The goal of the Small Molecule Discovery Core (SMD) is to help the Cancer Center and other investigators initiate drug discovery and chemical biology projects for their most innovative and exciting new targets. Faculty co-directors Adam Renslo, PhD and Michelle Arkin, PhD, both of UCSF’s
New 'SLICE' Tool Can Massively Expand Immune System's Cancer-Fighting Repertoire
Immunotherapy can cure some cancers that until fairly recently were considered fatal. In addition to developing drugs that boost the immune system’s cancer-fighting abilities, scientists are becoming expert at manipulating a patient’s own immune cells, turning them into cancer-killing armies. But
Get To Know: Tung Nguyen, MD
Dr. Tung Nguyen is the Stephen J. McPhee, MD Endowed Chair in General Internal Medicine and Professor of Medicine at the University of California, San Francisco (UCSF). A general internist with a large panel of Asian American patients, Dr. Nguyen teaches medical students and residents about medicine
Less Surveillance Needed for Simple Ovarian Cysts
Simple ovarian cysts are extremely common in women and do not require additional ultrasound surveillance or surgical removal, according to a new study of more than 72,000 women and close to 119,00 pelvic ultrasound exams over a dozen years. The study, a collaboration between UC San Francisco and
Cognitive Decline After Radiation Therapy for Brain Tumors Might Be Prevented By Temporarily Shutting Down Immune Response
Treating brain tumors comes at a steep cost, especially for children. More than half of patients who endure radiation therapy for these tumors experience irreversible cognitive decline, a side-effect that has particularly damaging consequences for younger patients. Up to now, scientists had been
"Orphan" RNAs Make Cancer Deadlier, But Potentially Easier to Diagnose
Scientists have long known that cancer can hijack a cell’s existing regulatory circuitry and transform healthy cells into deadly malignancies. But a new discovery from UC San Francisco demonstrates that cancer is more than just a mutineer that seizes control of the cell’s administrative operations —
As teen use of Juul soars, doctors ask, what's really in these e-cigs?
Tobacco research from UCSF is central to a growing understanding of the dangers of e-cigarettes and vaping products, as highlighted in this feature from NBC News. Dr. Mark Rubinstein, who studies nicotine dependence in adolescents at the University of California San Francisco, led the Teen Vaping