Jeroen Roose, PhD
Professor, Department of Anatomy, UCSF
Our cancer research program concentrates on understanding and interfering with cancer cell fitness. We investigate cancer-host cell interactions and capitalize on our biobanked cancer organoids and combination of epithelial cell biology and immunology.
Jeroen Roose is a tenured Principal Investigator and Vice Chair of Anatomy at the University of California, San Francisco. He is also a co-founder of UCSF's Bakar ImmunoX Immunology Program, co-lead of UCSF’s AutoIPI(AutoImmunoProfiler), and co-lead on the UCSF Endeavor program. During his PhD, he trained with Professor Hans Clevers and investigated Wnt signaling in cancer. His postdoctoral training with Professor Arthur Weiss focused on Ras signaling in T lymphocytes. Dr. Roose also runs an organoid disease to biology unit connected to UCSF's CoLabs. Dr. Roose has advisory functions for the Mark Foundation for Cancer Research.
The Roose lab as a whole focuses on understanding cell fate decisions and cell fitness driven by cell-cell interactions and signaling pathways, in the context of cancer, autoimmune diseases, and COVID-19. By taking a collaborative approach working with biophysicists, computational engineers, geneticists, and many clinicians, the Roose research team spans the gamut from fundamental to pre-clinical science. There is a rich training environment for staff, students, postdocs, and fellows in the established infrastructure of the Roose lab and the programs it is connected to. Jeroen Roose is a recipient of multiple grants and awards including support from the NIH, foundations, philanthropy, and industry.
For more information on research directions, projects, and publications, please visit our website at rooselab.ucsf.edu or at Roose Lab UCSF (@roose_jeroen) / Twitter
University of Utrecht, The Netherlands, MS, 1993, Medical Biology
University of Utrecht, The Netherlands, PhD, 1999, Immunology/Transcription
University of Utrecht, The Netherlands, Fellowship, 1997-1999, Immunology/Transcription
University of California San Francisco, San Francisco, Fellowship, 1999-2004, Immunology/Signaling