Human Proteins Behind COVID-19 Infection Revealed by Innovative CRISPR Technology

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host’s

Sorting Cancers by ‘Immune Archetypes’ May Offer New Approach For Precision Immunotherapies

Using data from over 300 patient tumors, UC San Francisco researchers have described 12 classes of “immune archetypes” to classify cancer tumors. Their findings, published this week in CELL, reveal that cancers from different parts of the body are immunologically similar to one another. These

Alpha Coronavirus Variant Evolved to Evade Immune System

The Alpha variant of SARS-CoV-2 – the first variant of concern – evolved mutations that allowed it to more efficiently suppress the immune system’s early response to infection, according to a new study led by scientists at the UC San Francisco’s Quantitative Biosciences Institute (QBI) and

Surgical Procedure Helps Cancer Patients Face Themselves Again

For patients undergoing facial reconstruction following disfiguring cancer operations, a new technique pioneered by surgeons at UC San Francisco may enable them to look more like their former selves. Typically, the use of skin from other parts of the body for facial skin reconstruction, has led to

Year In Review: 2021

International Breast Cancer Conference Features UCSF Health Experts

Experts from UCSF Health will present new research and clinical findings at the annual San Antonio Breast Cancer Symposium, the world’s largest and most prestigious breast cancer conference. This year’s meeting will be held Dec. 7-10. The international conference is expected to draw 8,000 attendees

$6M Gift from Family of Roblox Creator Launches New Initiative to Advance CAR T Therapy

UC San Francisco has launched the Baszucki Lymphoma Therapeutics Initiative to increase the effectiveness and availability of chimeric antigen receptor T-cell (CAR T) therapy for lymphoma patients. Jan Ellison Baszucki and her husband, Roblox CEO David Baszucki, gifted $6 million over five years to